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Breast-cancer-screening

Aspirin cuts breast cancer risk

Washington: A new study has shown that postmenopausal women who take aspirin and other analgesics regularly have lower estrogen levels, which could contribute to a decreased risk of breast or ovarian cancer.

“We observed some significant inverse associations between concentrations of several estrogens and the use of aspirin, aspirin plus non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs), and all analgesics combined,” said Margaret A. Gates, Sc.D., research fellow at the Channing Laboratory at Brigham and Women’s Hospital and Harvard Medical School.

“Our results suggest that among postmenopausal women, regular users of aspirin and other analgesics may have lower estrogen levels than non-users,” Gates added.

Gates and colleagues examined the association between use of aspirin, NSAIDs and acetaminophen and concentrations of estrogens and androgens among 740 postmenopausal women who participated in the Nurses” Health Study.

Frequency of all analgesic use was inversely associated with estradiol, free estradiol, estrone sulfate and the ratio of estradiol to testosterone.

Average estradiol levels were 10.5 percent lower among women who regularly used aspirin or non-aspirin NSAIDs. Similarly, free estradiol levels were 10.6 per cent lower and estrone sulfate levels were 11.1 percent lower among regular users of aspirin or other NSAIDs.

Among regular users of any analgesic (aspirin, NSAIDs or acetaminophen), levels of these hormones were 15.2 per cent, 12.9 per cent and 12.6 per cent lower, respectively, according to Gates.

These study results are published in ‘Cancer Epidemiology, Biomarkers & Prevention, a journal of the American Association for Cancer Research.’

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Breast cancer: how to recognize it?

Breast cancer: how to recognize it?

how-to-recognize-breast-cancerExceptional human breast cancer is the most common cancer in women. Exceptional in humans, breast cancer is the most common cancer in women, with 42 000 new cases each year . Breast cancer will affect a woman on eight of his life. Breast cancer affects one woman in eight during his life.

Risk Factors some risk factors could be identified (a woman presenting these factors will be more risk than another of developing breast cancer). Some risk factors have been identified (a woman with these factors will have a higher risk of developing breast cancer another).

Breast cancer screening first, most it advance in age, the risk is high: two-thirds of these cancers occur actually after 50 years. First, the more we advance in age, the greater the risk is high: two thirds of these cancers actually occur after 50 years.

Family history then: the breast of a first degree parent, mother or sister, multiplies the risk by fifteen. The family history then a cancer in a first degree relative, mother or sister increases the risk by five.

Hereditary cancers are rare: only 5 % of women with breast cancer are bearers of a genetic predisposition they transmit their daughters. [click to continue…]

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